In addition, such a variant of IRSI was also inhibiting the expansion of fat tissue. With no place to go, more fat was hanging around in the blood causing health issues.

However those with another variant of IRSI gene were really able to expand their fat tissue and though this tends to their seeming obese, they were healthier as their fat in their blood was removed and stored as it was meant to be, as body fat.

Genes that increase your risk of obesity can also protect you from Type-2 diabetes and cardiovascular disease and give you an optimal disease profile. These can be called healthy obesity genes, allowing storage of fat where it should be stored and protect the liver and muscles and against visceral fat.

The good news is, unless you have one of the very rare genetic mutations that undeniably cause excess obesity, your genes are just one factor in your weight profile.

Researchers estimate that obesity related genes account for just 3 percent of the differences between people sizes – and those same genes, that predispose people to gain weight existed 30 or even 100 years ago, suggesting that genes alone cannot explain the rapid rise in obesity.

In the end, your daily actions matter more. How much you decide to eat, what you eat and how much you choose to exercise, will in the majority of cases, trump your genes. However this is not the end of the story, other genes in our body also count. (See – ‘Gut Micro Flora and Obesity’).

“You may be genetically susceptible to become obese, but it doesn’t mean that you are destined to become obese” – Loos.

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